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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1dfd2a0b98b2d8cf6b05d900bc189030b4134f1d49a591ec052d01b22b2e78a' 
  AND token = '9+MtqOlgFDWC8O6pFSkh4WvaLsMeqFLlotT2zZZ43Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}