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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a2369a1893a9278cd1fa118eefc9e95eaf17ac2fad7c1a2546ffbf5db8843e5' 
  AND token = 'eUIc1vAFnfIG5d553XtBA9NYyM1JE18rQr9EQ9U2l74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}