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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c374dd84bac7a281f73eb47005a4b8e24ae6a8f69961b3c244e471cf342ffa4f' 
  AND token = 'ZbxTYrN7uHA4reJ9z0nweF6uZ+GQwdy8MtZgnrfgDeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}