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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd8ca1ac27f435b2d4e8dbd4eeca80ccf40ad7b770356adf51bedb980651e83a' 
  AND token = 'JUPvtnQ5CfHRX65dcN3A09A+tbqpukgpRqGY0lu/uGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}