SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01fd457bb9d4eac9fc30449f2b63a32b655f31eb6ae65b84e17d3ada2abcf2b2' 
  AND token = '8LMxKazLxnoGVaNTjLG4YcFFrzbEWx9lPVbtGxR69zE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}