SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '900fdbb262860a7b03429725c2c6a7b79d8bf6468b6db8867ada5af026b457de' 
  AND token = 'zcksVnR14BprCadSB2PcDoeOuDGToPVfNdgAr+MJakE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}