SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06c58aa5126b57f1b26914d0f8d2ea4ce7592ccc26e0c4a832bcf4a054d2c5fb' 
  AND token = 'S+CwTUjp3sstco0B1A6o3dYsZ+qLZXmbr7YqC6CcVxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}