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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce74d5a224658494b3934afd0f5d0d66556f170470bfb170f46aeee17d6999d2' 
  AND token = '5Hbo7F7S5s7CDQjSWgsZf69GTnlYBbm/2roGSY43S24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}