SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87cd892bc0d754387b0f3e43c69af6110cad1675a6ce7e62ed68b366d961181f' 
  AND token = 'OOO2+IMHWx0Q0ZSal96rFcBBrMdJ74Gw1bWfwOQvSXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}