SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33b81a1d9fcde6bbdcab793139ed64cd9c646b695b1cfb0e940a5af913fb5e75' 
  AND token = 'ZXChCChkB3C3rpyiGmQoKoo/WYvhzoOyt9ZJ6VfcFn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}