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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e9e54e6bdd4b20f043a8366f0f6890e8c8bd3cc63805978deb233fb7eb4e07e' 
  AND token = 'alt0d3e3vz4r5awwu+HzalTYZFK/RVZIoCsbOIGYeus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}