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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4331fea48b8396e949056d6c63dce7f4c5049ded0ffac40c66f0b768dc995202' 
  AND token = 'YEDSmOFtX0g8BvGepKBd9pq7MQfFbfPyxYC2mCOkQzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}