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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf5c16ac08bfa08e3ab935a8a0bcc0b1b07e4476975c3b9fc022885aa1abbeb' 
  AND token = 'gktzck+emcQCCCTO9BHPNnotu9uhEFWPsYl+isgUR9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}