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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef825ad43e6c01a9428eabb14ff1946cbd527057d79517764083971be474702a' 
  AND token = 'JGP/RoEAKtnaXV4OJa5OH5T7650ORdA/NCi6wjzmV00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}