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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3518626512ca1a0c25b2441e8afd34eba7ea6128752ee78aba89686f5904a226' 
  AND token = 'sGrWUWUw26AXCCynoQ+98KzVL88oTaG5yl2O+h0xSrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}