SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a65cb0eca96890fc4122a92824adda84fa01a4196a4ba17bd8000258e578ddb' 
  AND token = 'yN2ykPnM0Z5hWiOhtsnaVig3kReY0uh4EZ9UihkB1rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}