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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a06e2f49d7a85a7dc185ec3c0b370007967661c9cff4cfb1da8b4c10623774' 
  AND token = '5kGzYJeI8dI9dDVeshkVIVLx5cvLzT78RtRcT3Z/2mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}