SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dcb0bdce2f079f384875130870caf3e2b30cd4ceaf6d8041e7d44a98f455a15' 
  AND token = 'Nd1EL/wVqsay8aKO6VsW/kPcw96qeebcgWY+KP+VbPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}