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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89657fe3b4b640e0678894c791e97e303153e12e80610ffc0c26deee900602a7' 
  AND token = 'pu9YN+EnYwJeOaOlulw2/xo8OiBcrlGsTCB66eBuLqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}