SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d60369dda67704ff07e19947009209cc41ede8df5fa9eceb77401207e3dfbeb' 
  AND token = 'sZxw7YLQybc5NsmsxRvAjZpaVjk1SbtFS8pZTJeYhY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}