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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4368e8f1b3e2360fdf1dfedf1881c3281e9cd587efb928c111f1211453ceea60' 
  AND token = 'Yu8xxHlqTGeLRoCLQtot4BReZNt4zMSEGHFbMF6+9rY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}