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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9c3883b5368769af817f22c3b95bdc0a06d3d7b73232e95da65c91bf1fb7d4' 
  AND token = 'QO5wjx0CHNIxq/ToZo5pkep8cKNMqiozAUz5YQz6t64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}