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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25bc66ff14ef5901f3d30c1e95353ac315e96c96d425d510aaad6cdafd851a44' 
  AND token = 'TxguWbREr+BnPZqECaqU1i5SiE0emkzIfKSUBAwRy1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}