SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c7ce554ac09e73c0060b9a0c338a5dcface88533fcc957fec15d15d3d3b02db' 
  AND token = 'E4MxoXIB288H8G7ZYTobqASsiyethy1Ap/aaYOr8tls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}