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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4fd8321844f460d0df38be272c0a1d4baf6de939e7917c6415601a47b4fbd70' 
  AND token = '7PD3LwFMBkBZSO5zXXa9i57FLh7mvo+PpQxWA7c7j9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}