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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0b55cc5f22c29979c7fbf90ced6b31ab1c0db7505fad2eee82d7511aa4cb379' 
  AND token = '1FpzhoUGBtSxszRC3vUpAUDe8eBYZggBGf3TM7eYjtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}