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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b6f59105770b0f528446d479af3c4115cafe52c0f972c3d5fdf3936d3adc43' 
  AND token = 'flhqv2/OzDIO5BoPiSmkRhGiN8cRk+czhzleT62rYkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}