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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f7695cc8effc79a1fa465972f8addc6f478d7ed89504913d689be7c859400e7' 
  AND token = 'XQ3j0aW48FZB9HbW9Yt/sNkq4L8zZ6/yT/6gzFvsZYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}