SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf2b64d6a16a345524c17b9c1766387ef118531d63501261180c6d6fe4a754d1' 
  AND token = '1jDiDoqUauPrWtDd+wNBLZlh5iEDODC3iYzRhDLCHPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}