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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c789905e3b23d280f9cb46eccb7278c3d35b6e8af066551edbb9c050bfd42674' 
  AND token = 'm85lieZelZ7M+GWpQw8kOZyylSJDu7+V9y5C69YmSpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}