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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85045a7c651167a85721911c2691f25d745ef0a95fc3e005601d5ccdb3b3a38f' 
  AND token = 'IWyWJSmriyai4xQQQVnwjBvyqgnFm4x61OSi/qwfUoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}