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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8578ee2280228aa3a52f420f57f3a10c5a540b88600d518ce4cc787ae7257c8' 
  AND token = 'l76CxSu71CjpFwfRqNJ5mrpXUzJBwtyGd2DciZLt7Eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}