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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dddd27f07283e38ae403a7dde10d86a12a7e79e83b3171dee2fffb8483279a05' 
  AND token = '+u1pLWmH1glqPVX85fdmLHJ0QX+4eEUVjS36sX17Ar4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}