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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0443c416a6d6514d799272a4baa4e008f65cb63d3f7e1bbb3bb60b818d5a560' 
  AND token = 'Iog+K9gpM3UFXVTI1I7HcVTd90fkcYGEEWP3WZI2Tn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}