SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9524442cc6fd109ec274bb8a31a27a260dcd2acfb09c98036210f4de5299fcab' 
  AND token = 'xoQdvmutwelRk78vNH8L+tzS+bHIVnfLbQpYdLMZlG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}