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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4c5407f1e7dd1fff6264f6593f60190ffee07a68d0640aa59577abcb354be03' 
  AND token = 'UXbgQldyJTifiL8053l4U9fceplJzXyxB0S+knhN+Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}