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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7688259c6f5ccced94d06f94fae6fd91911f9258982046c64f2f43fadcfdd6ca' 
  AND token = 'CTmmFssbyOiYwavooNo3TDclTWRD2FsdXT6NFZRBYwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}