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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb3bb1b702f86abbd16d1c19ab3d4e72e679d72e2fcddb40cc0c46619342383' 
  AND token = 'XQ6JbMHQWfjVhxdVHAMvL5tyc0notiXvMz0MPzDARlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}