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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5d12e48fd91a67f1516efdda136d06e6a5854f3eedc5eb2dd85283cb20f354c' 
  AND token = 'wlr8zzJMCuboPPtDPL9bmTfFWrbsXZwdYtteq2WWaJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}