SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bbac215efa5b1fcee2c84d786ce0e36cfddd9c25659e976c99539a6bde90778' 
  AND token = 'KDU7woIaDltvI6WAS+74VxQVaw4kKJr0J2TFPtlaFSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}