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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b45544a4bd90244d09c452b1ffc3129be016b48a5a2b909d1f8c170c960aa69' 
  AND token = 'z+qj6TXPmNmvA8OkMaoILmRGDGHGF6EWieXdoONcQo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}