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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6f2aee1919c0d86788e04efc1c64cb800393b2cd05a5fdb5664e94c21955a17' 
  AND token = 'ixVYFJmE3EL1Dxth47n9GrsuJ9pNKmbkbji+MgpJN9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}