SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372eafbf0d2250fc256871a34327ff95ebbe6b89ec1f44b3920892d58c5e188e' 
  AND token = '5gXzKUz1OHQttSFLvWTNYhPxP15g1M8TRMie2/t5u2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}