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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c181749cbc9e8c16bfd321cfd5f032c3e08b5b5968cfbef8c3ec5c378c7ca49' 
  AND token = 'iWSDcl6pU2adA2+KAyHvNzjYnhCy6UjcqHGvN4EK7zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}