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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5090ed17aedb76e7bff5598f8419e6552c367d9aa9dec4afd89d84012fed877b' 
  AND token = '0wImWs5FR+Qc2V+ou8q5EWHeB4+v9yTFPKW8ONrC8cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}