SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75393375e020ee177cacad7c422c8e095848aa93bf60d92723e2c5d4c051a4ef' 
  AND token = 'UK1+WvSNGyR1e29MAUm83kZkKx0EKi7eL/XRpOeopT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}