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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ac05875e28e496031438ba3f78d0d2f76b59b15aa70bd236a8c666f9ba05b83' 
  AND token = 'RANv2KB5Iatl+Ve1JyJMfnpjVHFPWNYyPNf32Hjnl3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}