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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381ab8f662ab4da39dc4e8ff97b871488416b08df1594d0b11cc5b1da384ba55' 
  AND token = 'sHNisp5wACDJWNeL1rQhcDG3/witcDHDJncaNQwNZZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}