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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73963f26050b4cf61ea654eb2b3c4fd2b9ece5af9b39e119ddc792a7b098b280' 
  AND token = 'YE0NZyFW3DTpx9oV6gC0qpu0lf19tdMaLatcQqL/QsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}