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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f30f5349e21276b97248b10dfc9011815d3dac691e343feed79933fb827269' 
  AND token = 'Np3wJRkdTg/V4NhRPcrBi9zlNlb47Uxrivq1o7CXuzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}